diff --git a/nova/conductor/tasks/live_migrate.py b/nova/conductor/tasks/live_migrate.py
index cf53353195..acea49228e 100644
--- a/nova/conductor/tasks/live_migrate.py
+++ b/nova/conductor/tasks/live_migrate.py
@@ -241,6 +241,22 @@ class LiveMigrationTask(base.TaskBase):
                        "source and destination nodes do not support "
                        "the operation.")
 
+    def _check_can_migrate_specific_resources(self):
+        """Checks that an instance can migrate with specific resources.
+
+        For virtual persistent memory resource:
+            1. check if Instance contains vpmem resources
+            2. check if live migration with vpmem is supported
+        """
+        if not self.instance.resources:
+            return
+
+        for resource in self.instance.resources:
+            if resource.resource_class.startswith("CUSTOM_PMEM_NAMESPACE_"):
+                raise exception.MigrationPreCheckError(
+                    reason="Cannot live migration with virtual persistent "
+                           "memory, the operation is not supported.")
+
     def _check_host_is_up(self, host):
         service = objects.Service.get_by_compute_host(self.context, host)
 
@@ -322,6 +338,7 @@ class LiveMigrationTask(base.TaskBase):
         return source_info, destination_info
 
     def _call_livem_checks_on_host(self, destination, provider_mapping):
+        self._check_can_migrate_specific_resources()
         self._check_can_migrate_pci(self.source, destination)
         try:
             self.migrate_data = self.compute_rpcapi.\
diff --git a/nova/tests/unit/conductor/tasks/test_live_migrate.py b/nova/tests/unit/conductor/tasks/test_live_migrate.py
index 7539e47f47..acf282c8de 100644
--- a/nova/tests/unit/conductor/tasks/test_live_migrate.py
+++ b/nova/tests/unit/conductor/tasks/test_live_migrate.py
@@ -61,6 +61,7 @@ class LiveMigrationTaskTestCase(test.NoDBTestCase):
         self.instance.system_metadata = {'image_hw_disk_bus': 'scsi'}
         self.instance.numa_topology = None
         self.instance.pci_requests = None
+        self.instance.resources = None
         self.destination = "destination"
         self.block_migration = "bm"
         self.disk_over_commit = "doc"
@@ -858,3 +859,16 @@ class LiveMigrationTaskTestCase(test.NoDBTestCase):
                           _test, pci_requests, False, True)
         self.assertRaises(exception.MigrationPreCheckError,
                           _test, pci_requests, True, True)
+
+    def test_check_can_migrate_specific_resources(self):
+        vpmem_0 = objects.LibvirtVPMEMDevice(
+            label='4GB', name='ns_0', devpath='/dev/dax0.0',
+            size=4292870144, align=2097152)
+        resource_0 = objects.Resource(
+            provider_uuid=uuids.rp,
+            resource_class="CUSTOM_PMEM_NAMESPACE_4GB",
+            identifier='ns_0', metadata=vpmem_0)
+        self.instance.resources = objects.ResourceList(
+            objects=[resource_0])
+        self.assertRaises(exception.MigrationPreCheckError,
+                          self.task._check_can_migrate_specific_resources)